and minimal biohazard (all waste stays
onboard). The system weighs about 2 kg,
with dimensions of 12 ; 8 ; 20 cm.
Preliminary findings from the study,
presented at the 2012 Conference on
Retroviruses and Opportunistic Infections
held in Seattle in March, showed that the
system had “minimal bias” relative to the
gold standard, flow cytometry – thus underscoring the potential of the system for
Imaging in the developing world
Tricorder-like devices – particularly optics-based ones – can also contribute to a
host of global health applications. There
is little access in developing nations to
the sophisticated lab tests and the training
needed to run them that can be commonplace in the developed world.
Health care workers use a variety of inexpensive, portable tests to meet the many
global health demands they face, but these
can have limited efficacy. In recent years,
researchers and medical device companies
have shown that optics-based technologies
can bridge this gap.
Take, for example, rapid diagnostic
tests (RDTs) – assays designed to detect
target analytes in blood or fluid samples.
Using RDTs, and with only minimal training, health care workers have been able to
detect a range of diseases – including
HIV, malaria, tuberculosis and syphilis –
leading to better management of disease
and more efficient surveillance of outbreaks.
Conventional RDTs have their limitations, though. Because they are read manually, there is potential for error, especially
as the workers often administer a variety
of different tests at the same time. Cell-phone-based, tricorder-like devices could
help to eliminate this potential for error by
offering automated readings of the diagnostic tests.
At the annual conference of the American Association for Clinical Chemistry
held in Los Angeles in July, Holomic LLC
– a company launched in 2011 to commercialize the biophotonic technologies invented in Aydogan Ozcan’s lab at UCLA –
introduced its cell-phone-based rapid
diagnostic test reader, the HRDT-1.
Weighing only about 65 g, the device
mechanically attaches to the existing camera
unit of a cell phone. An app on the phone
digitally processes captured images – within
0.2 s per image – then provides a reading of
the diagnosis, and finally sends the image
and accompanying data to a central server.
New Bench-Top Fluorometer
The world’s fastest and most sensitive integrated bench-top luminescence spectrometer
This 3-D matrix of wavelength vs μs decay was
acquired in just 15 seconds!
Quattro™ unique benefits
5 femtomolar fluorescein spectral detection limit!
Phosphorescence decays collected from a single 1 μs flash!
3-D matrix of wavelength versus decay acquired in seconds!
Unique lifetime-based reaction kinetics!
There has never been a bench-top luminescence spectrometer that could offer a single one
of these unique benefits, let alone all four. Now, with the introduction of the all-new Quattro™
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OPTICAL BUILDING BLOCKS CORPORATION